Key Research Articles on the tumor microenvironment, cancer progression, dormancy and metastasis:

Borriello L, Coste A, Traub B, Sharma V, Karagiannis GS, Yu L, Wang Y, Ye X, Duran C, Chen X, Friedman M, Sosa MS, Sun D, Dalla E, Singh Deepak, Oktay M, Aguirre-Ghiso J*, Condeelis JS*, Entenberg D*. Primary Tumor Associated Macrophages Activate Programs of Invasion and Dormancy in Disseminating Tumor Cells. Nature Communications, 2022 Feb 2;13(1):626.

Borriello L, Condeelis JS, Entenberg D, Oktay M. Breast Cancer Cell Re-Dissemination From Lung Metastases – a Mechanism for Enhancing Metastatic Burden. Journal of Clinical Medicine,2021. 27;10(11):2340.

SharmaV, TangB, Wang Y, KaragiannisG, XueE, EntenbergD, Borriello L, CosteA, Duran C, Eddy R, Kim G, Ye X, Jones J, Grunblatt E, Agi N, Roy S, Bandyopadhyaya G, Adler E, Surve C, Esposito D, Goswami S, Guo W, CondeelisJS,WakefieldL, OktayM. Live Imaging of Breast Tumors Shows Macrophage-Dependent Induction and TMEM-Mediated Enrichment of Cancer Stem Cells during Metastatic Dissemination. Nature Communications, 2021. Dec 15;12(1):7300

Borriello L, Nakata R, Shear MA, Fernandez E, Seeger R, Malvar J, Blavier L, Shimada H, Asgharzadeh S, Seeger R and DeClerck YA. Cancer-Associated Fibroblasts Share the Characteristics and Protumorigenic Activity of Mesenchymal Stromal Cells. Cancer Research,2017. 15;77(18):5142-5157. 

Hadjidaniel M, Muthugounder S, Hung L, Shirinbak S, Chan R, Nakata R, Borriello L, Sheard M, Iwakura H, Akamizu T, Shimada H, Sposto R, DeClerck YA, Asgharzadeh S. Tumor Associated Macrophages Promote Tumor Growth Independent of IL6 in Murine Model of Neuroblastoma. Oncotarget,2017.16;8(53):91516-91529.

LifshitzV, PricemanS, LiW, CherryholmesG, LeeH, Makovski A, BorrielloL, DeClerckY, YuH. Sphingosine-1-Phosphate Receptor-1 Promotes Environment-Mediated and Acquired Chemoresistance. Molecular Cancer Therapy,2017.16(11):2516-2527. 

Solari V, Borriello L, Turcatel G, Shimada H, Sposto R, Fernandez GE, Asgharzadeh S, Yates EA, Turnbull JE, DeClerck YA. MYCN-Dependent Expression of Sulfatase-2 Regulates Neuroblastoma Cell Survival. Cancer Research, 2014.1;74(21):5999-6009.  

Major Review Articles on the tumor microenvironment, cancer progression, dormancy and metastasis:

Duran C, Borriello L, Karagiannis G, Entenberg D, Oktay M, Condeelis JS. Targeting Tie2 in the tumor microenvironment: from angiogenesis to dissemination. Cancers, 2021. Nov 16;13(22):5730.

Borriello L*, Karagiannis GS, Duran C, Coste A, Oktay M, Entenberg D* and Condeelis JS*. The Role of the Tumor Microenvironment in Tumor Cell Intravasation and Dissemination. *Corresponding authors – European Journal of Cell Biology, 2020. 99(6):151098.  

Sanchez LR, Borriello L, Entenberg D, Oktay M, Condeelis JS, Karagiannis G. The Emerging Roles of Macrophages in Cancer Metastasis and Response to Chemotherapy. Journal of Leukocyte Biology,2019.106(2):259-274. PMID: 30720887

Zijlstra A, Von Lersner A, Yu D, Borriello L, Oudin M, Kang Y, Sahai E, Fingleton B, Stein U, Cox T, Price J, Kato Y, Welm A, Aguirre-Ghiso A. The Importance of Developing Therapies Targeting the Biological Spectrum of Metastatic Disease. Clinical and Experimental Metastasis,2019. 36(4):305-309. PMID: 31102066.

Borriello L, Seeger RC, Asgharzadeh S, DeClerck YA. More Than the Genes, the Tumor Microenvironment in Neuroblastoma. Cancer Letters, 2015.S0304-3835(15)00693. PMID: 26597947. 

Borriello L and DeClerck Yves. Tumor Microenvironment and Therapeutic Resistance Process. Medecine Sciences, 2014.30(4):445-51. PMID: 24801042.

Key articles on the intravital lung imaging:

Borriello L, Traub B, Oktay M, Entenberg D. A Permanent Window for Investigating Cancer Metastasis to the Lung. Jove, 2021. Jul 1;(173). doi: 10.3791/62761. 

Entenberg D, Voiculescu S, Guo P, Borriello L, Wang Y, Karagiannis GS, Jones J, Baccay F, Oktay M, Condeelis J. A Permanent Window for the Murine Lung Enables High-Resolution Imaging of Cancer Metastasis. Nature Methods, 2018. 15(1):73-80.